Zeta potential messung


Startseite / Geschichte, Wissenschaft & Bildung / Zeta potential messung


Its measurement brings detailed insight into the causes of dispersion, aggregation or flocculation, and can be applied to improve the formulation of dispersions, emulsions and suspensions. Sie gibt uns aufschluss darüber, wie stabil eine suspension oder emulsion voraussichtlich sein wird.

Zeta potential is a measure of the electrical charge that exists on the surface of microscopic particles when they are suspended in a liquid medium. Letztendlich liefert die zeta-potential-messung wertvolle einblicke für die qualitätskontrolle und prozessoptimierung.

This electrical property is expressed in millivolts (mV). Ein höherer negativer oder positiver wert deutet generell auf eine bessere stabilität hin, da sich gleich geladene partikel abstoßen. The zeta potential of colloidal dispersions influences various properties, including stability, rheology, and interactions with other molecules or surfaces.

Durch die beobachtung von änderungen des zeta-potentials können wir zum beispiel die effektivität von stabilisatoren oder flockungsmitteln beurteilen. For molecules and particles that are small enough, a high zeta potential will confer stability, i.e., the solution or dispersion will resist aggregation.

It ensures the uniform distribution of active ingredients and prevents phase separation or creaming, thereby enhancing product efficacy and shelf life.

Zeta potential

Verschiedene faktoren wie der ph-wert, die ionenstärke und die temperatur der dispersion können das zeta-potential stark beeinflussen. Sie hilft uns, produkte zu entwickeln, die nicht nur optisch ansprechend, sondern auch funktionell stabil sind.

Zeta potential is not a property of the particle but of the system, that is the particle and the medium it is dispersed in. Zeta potential analysis is vital in pharmaceutical formulations to assess the stability of drug suspensions, emulsions and liposomes.

As a rule of thumb the zeta potential value measured can be broadly classified in terms of the magnitude of the charge see table. Zeta potential measurements to improve formulation stability, shelf life and reduce formulation time and costs.

A charged particle will attract counter-ions which become more diffuse the further from the particle surface. The importance of this measurement type lies in its ability to predict and control the stability and performance of colloidal dispersions. Zeta potential analyzers, such as the Zetasizer Advance, utilize a technique called electrophoretic light scattering sometimes known as laser Doppler velocimetry to determine the zeta potential of a wide range of colloidal and dispersed systems, such as metal oxides, proteins, liposomes, emulsions and so on.


Die zeta-potential-messung ist ein faszinierendes werkzeug, um die oberflächenladung von partikeln in einer flüssigkeit zu verstehen. In the cosmetics industry, zeta potential measurement aids in formulating stable emulsions, creams and lotions.

Understanding and controlling zeta potential is crucial in diverse applications such as drug delivery, food processing and coating formulations. Those counter-ions that travel with the particle define the slipping plane and its associated zeta potential.

This assay protocol outlines the procedure for sample preparation and determination of zeta potential. The magnitude of the zeta potential indicates the degree of electrostatic repulsion between adjacent, similarly charged particles in a dispersion.

Guidelines for making successful zeta potential measurements are provided, as well as a discussion of relevant standards and data analysis. Diese bewegungsgeschwindigkeit, die sogenannte elektrophorese, ist direkt proportional zum zeta-potential.

Diese technik findet breite anwendung in der kosmetik-, pharma-, lebensmittel- und farbenindustrie. By optimizing zeta potential, manufacturers can enhance product quality, shelf life and overall process efficiency. In each of these sectors, understanding and controlling zeta potential is crucial for optimizing product formulations, ensuring stability, and enhancing performance.

Zeta potential analysis is widely used across different industries where colloidal systems play a significant role. Zeta potential analysis is essential in food and beverage formulations to stabilize emulsions, suspensions, and colloidal systems.

It helps in optimizing drug delivery systems by controlling particle interactions and ensuring uniform dispersion. Changes to the medium, such as concentration of ions, types of ions and pH will all affect the zeta potential.

Measuring zeta potential is essential for understanding the behavior of colloidal systems. Die messung basiert oft auf der analyse der bewegungsgeschwindigkeit von partikeln unter dem einfluss eines elektrischen feldes. It helps in optimizing drug delivery systems by controlling particle interactions and ensuring uniform dispersion.

Zeta-Potential Messung

Daher ist es wichtig, diese parameter bei der messung genau zu kontrollieren. Negative zeta-potentiale sind in vielen anwendungen wünschenswert, um unerwünschte aggregation zu verhindern. When we measure zeta potential, we are measuring the electrical potential at the slipping plane of a particulate system.

Zeta potential analysis is vital in pharmaceutical formulations to assess the stability of drug suspensions, emulsions and liposomes.